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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKZ
All Species:
6.97
Human Site:
S268
Identified Species:
11.79
UniProt:
Q13574
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13574
NP_001099010.1
1117
124128
S268
P
G
A
P
C
S
E
S
E
R
Q
I
R
S
T
Chimpanzee
Pan troglodytes
XP_508395
1117
124129
S268
P
G
A
P
C
S
E
S
E
R
Q
I
R
S
T
Rhesus Macaque
Macaca mulatta
XP_001102461
1084
120447
P251
R
R
P
S
G
Q
H
P
G
P
G
G
R
R
A
Dog
Lupus familis
XP_540755
766
85714
T10
V
L
G
A
G
H
S
T
G
A
G
C
D
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
H173
R
E
P
T
F
V
R
H
H
W
V
H
R
R
R
Rat
Rattus norvegicus
O08560
929
103991
H173
R
E
P
T
F
V
R
H
H
W
V
H
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
P199
H
A
A
V
I
I
P
P
T
W
I
I
K
V
K
Chicken
Gallus gallus
NP_001026363
953
106222
K197
G
K
C
R
Q
C
G
K
G
F
Q
Q
K
F
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
S267
Q
Q
K
F
A
F
H
S
K
E
I
V
A
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
R533
V
P
N
I
N
A
T
R
S
R
S
V
D
I
V
Honey Bee
Apis mellifera
XP_396522
837
92900
S81
S
K
E
I
V
A
V
S
C
S
W
C
K
L
A
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
L181
A
D
H
W
R
K
A
L
A
K
S
P
V
V
R
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
A59
P
R
S
Q
S
M
G
A
A
A
L
Q
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.3
65.1
N.A.
78.2
79.3
N.A.
54.7
67.8
N.A.
60.4
N.A.
31.9
31.2
31.6
43.1
Protein Similarity:
100
99.8
91.2
66.6
N.A.
80.5
80.5
N.A.
65.8
74.8
N.A.
70.6
N.A.
46.1
46.2
46.3
55
P-Site Identity:
100
100
6.6
0
N.A.
6.6
6.6
N.A.
13.3
6.6
N.A.
6.6
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
100
6.6
6.6
N.A.
6.6
6.6
N.A.
20
13.3
N.A.
26.6
N.A.
20
20
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
22
8
8
15
8
8
15
15
0
0
8
0
29
% A
% Cys:
0
0
8
0
15
8
0
0
8
0
0
15
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
15
8
0
0
0
15
0
15
8
0
0
0
8
0
% E
% Phe:
0
0
0
8
15
8
0
0
0
8
0
0
0
8
0
% F
% Gly:
8
15
8
0
15
0
15
0
22
0
15
8
0
0
8
% G
% His:
8
0
8
0
0
8
15
15
15
0
0
15
0
0
0
% H
% Ile:
0
0
0
15
8
8
0
0
0
0
15
22
0
15
0
% I
% Lys:
0
15
8
0
0
8
0
8
8
8
0
0
22
0
8
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
22
8
22
15
0
0
8
15
0
8
0
8
0
0
0
% P
% Gln:
8
8
0
8
8
8
0
0
0
0
22
15
0
0
0
% Q
% Arg:
22
15
0
8
8
0
15
8
0
22
0
0
36
22
22
% R
% Ser:
8
0
8
8
8
15
8
29
8
8
15
0
8
22
8
% S
% Thr:
0
0
0
15
0
0
8
8
8
0
0
0
0
0
15
% T
% Val:
15
0
0
8
8
15
8
0
0
0
15
15
8
15
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
22
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _